The second season of Celebrity Blackjack followed the same format as the first season with a few notable exceptions.

- Only 4 celebrities were seated at each table.
- Two semi-final rounds were added to the tournament schedule.
- Five card charlie was added to the rules. The Five Card Charlie rule is when a player hits to a hand with five cards and does not bust they automatically win.

	Preliminary Round	Semi-Final Round	Championship Round
1	Jason Alexander Ricki Lake Jeff Probst Steve Howey
2	Jamie-Lynn DiScala Tori Spelling Gabrielle Reece Dave Navarro
3	Lance Bass Chris Harrison Kathy Najimy Kevin Hart
4	Cheryl Hines Coolio Meat Loaf Mathew St. Patrick
5	Shannon Elizabeth Gary Valentine Camryn Manheim Dayna Devon	Caroline Rhea Jeff Probst Kelli Williams John Henson Warren G.
6	Dennis Rodman Marissa Jaret Winokur Adam Carolla Giuliana DePandi	Jamie Lynn DiScala Jason Alexander Giuliana DePandi Lance Bass Coolio	Jason Alexander Kelli Williams Jeff Probst Lance Bass
7	John Henson David Higgins Steve Harris John Melendez
8	Caroline Rhea Billy Baldwin Stephen Baldwin Daniel Baldwin
9	Sara Rue Warren G. Carnie Wilson Ralphie May
10	Carrie Fisher Kelli Williams Eric Roberts Chynna Phillips
Jason Alexander won the tournament and $250,000 for his Charity